Blog
- Home
- Blog
Blog & Articles
The Difference Between 99 Percent and 99.9 Percent Is Not 0.9 Percent
Subtracting 99.0 from 99.9 gives an answer that is arithmetically correct and analytically..
What an HPLC Purity Number Actually Measures
An HPLC purity figure is a ratio of peak areas, not a ratio..
Levodopa and the Blood-Brain Barrier: A Molecule Designed Around a Transport Problem
PubChem gives levodopa a computed XLogP3 of -2.7 and dopamine -1.0, so the..
Cholinergic Precursors Compared: Alpha-GPC and Citicoline in the Literature
Human plasma after oral citicoline carries uridine, not cytidine, which is the reverse..
Methylene Blue: The First Fully Synthetic Drug and Its Second Life in the Laboratory
Synthesised in 1876 as a dye for cotton, methylene blue became the first..
AMPA Receptor Modulation: What Ampakines Do at the Molecular Level
A 2002 structure of GluR2 showed that stabilising the dimer interface reduces desensitisation...
From Piracetam to Aniracetam: What an Anisoyl Group Actually Changes
Swapping piracetam's acetamide arm for a 4-methoxybenzoyl substituent changes the nitrogen count, the..
The Racetams and Their Missing Mechanism: Fifty Years Without a Consensus
A 1994 review of 407 papers reported no accepted mechanism for the racetams...
Adamantane Chemistry: The Diamond Cage Behind Bromantane
A ten-carbon hydrocarbon that melts above 540 K, sublimes instead of boiling, and..
The Racetam Skeleton: Why 2-Oxo-1-Pyrrolidine Acetamide Became a Chemical Family
A five-membered lactam and a short acetamide arm are all that define the..
Modafinil and the Dopamine Transporter: What Imaging Studies Showed
A 1994 paper reported low-affinity binding at the dopamine uptake site; PET imaging..
Bromantane’s Dual Profile: Actoprotector Research from the Soviet Era
Forty-five of the fifty-six PubMed records naming this compound in the title carry..