Where Research Compounds Come From: Discovery, Synthesis and Structure
Accident, phenotypic screening, target-based design and metabolite follow-up put different kinds of molecule into the literature. This hub maps the routes, and decodes the lab code, the INN stem and the CAS Registry Number that follow a compound afterwards.
Modafinil’s Accidental Origins: How Adrafinil Led to a Simpler Molecule
Modafinil differs from adrafinil by a single oxygen atom, and it was never the target of a discovery programme. It was found by asking what the body did to the compound that came first.